There are several restrictions inherent to the McKetta-Wehe chart.
- This chart is suitable for sweet natural gas with a mole fraction of methane of more than 70%, and a relatively small fraction of heavy hydrocarbons.
- Water content is overestimated at pressures of 70 bar absolute and over.
- The correlation is not suitable for natural gas in equilibrium with gas hydrates. The water content of these is a complex function of their composition and time. Thus few reliable correlations exist, and thermodynamic models are usually used.
- The McKetta-Wehe chart should only be used at temperatures below which hydrate would form.